Spectroscopy Group of Basque Country University Structural study of biological molecules in the gas phase using Microwave Spectroscopy
We studied the impact of the aliphatic side chain in the stability and conformational landscape of the local anaesthetics benzocaine, butamben and isobutamben, combining high resolution rotational spectroscopy in the microwave and millimetre regions and quantum-mechanical calculations. The study reveals the connections between the alkyl chain flexibility and molecular conformations.
The paper has been accepted by Chemical Communications.
