The structure of antipyretics: phenazone

The conformational and structural preferences of phenazone (antipyrine), the prototype of non-opioid pyrazolone antipyretics, have been published in The Journal of Chemical Physics.

The spectrum exhibited very complicated fine and hyperfine patterns originated by the simultaneous coupling of the methyl group internal rotation and the spins of the two 14N nuclei with the overall rotation.

Phenzazone

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